A Lifetime of Exercise Slows Down Ageing

Acupuncture in Exeter: A lifetime of exercise slows down ageing. Researchers at the University of Birmingham and King’s College London have found that staying active keeps the body young and healthy. They set out to assess the health of older adults who had been active most of their adult lives to see whether exercise slows down ageing.

The study recruited 125 amateur cyclists aged 55 to 79, 84 of whom were male and 41 were female. The men had to be able to cycle 100 km in under 6.5 hours, while the women had to be able to cycle 60 km in 5.5 hours. Smokers, heavy drinkers and those with high blood pressure or other health conditions were excluded from the study. Participants underwent a series of tests, and were compared to a group of adults who did not partake in regular physical activity. This group consisted of 75 healthy people aged 57 to 80 and 55 healthy young adults aged 20 to 36.

As expected, the study showed that loss of muscle mass and strength did not occur in those who exercised regularly. The cyclists also did not increase their body fat or cholesterol levels with age and the men’s testosterone levels remained high. More surprisingly though, the study revealed that the benefits of exercise extend beyond muscle as the cyclists had an immune system that did not seem to have aged either. An organ called the thymus, which makes immune cells called T cells, starts to shrink from the age of 20 and makes fewer T cells. In this study however, the cyclists’ thymuses were making as many T cells as those of a young person.

Professor Janet Lord, Director of the Institute of Inflammation and Ageing at the University of Birmingham, said, “Hippocrates in 400 BC said that exercise is man’s best medicine, but his message has been lost over time and we are an increasingly sedentary society. Our research means we now have strong evidence that encouraging people to commit to regular exercise throughout their lives is a viable solution to the problem that we are living longer but not healthier.”

Norman Lazarus, Emeritus Professor at King’s College London and Dr Ross Pollock, who undertook the muscle study, suggested, “Find an exercise that you enjoy in whatever environment that suits you and make a habit of physical activity. You will reap the rewards in later life by enjoying an independent and productive old age.”

(Properties of the vastus lateralis muscle in relation to age and physiological function in master cyclists aged 55–79 years. Aging Cell, 8 March 2018.

Major features of Immunesenescence, including Thymic atrophy, are ameliorated by high levels of physical activity in adulthood. Aging Cell, 8 March 2018.)

Healthy Weight & Further Education assist with a Long Lifespan

A major new study by researchers at the University of Edinburgh, indicates that maintaining a healthy weight and continuing in further education, are two of the best behaviours to adopt to extend our lifespan. Data was drawn from 25 separate population studies mainly across Europe, Australia and North America. For each year spent studying beyond school, 11 months was added to lifespan. Giving up smoking and being open to new experiences also seem helpful. However, for people who are overweight, each extra kilogramme of body weight is associated with two months off their lifespan. The study identified two new DNA differences which affect lifespan: a gene linked to the immune system adds around half a year to life expectancy whilst one linked to blood cholesterol levels shortens it by around eight months.

Dr Peter Joshi, Chancellor’s Fellow at the University of Edinburgh’s Usher Institute, said: “Our study has estimated the causal effect of lifestyle choices. We found that, on average, smoking a pack a day reduces lifespan by seven years, whilst losing one kilogram of weight will increase your lifespan by two months.”

(Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nature Communications, on-line 13 October 2017.)

Gardening and Health

Acupuncture in Exeter: gardening and health.In NGS National Gardens and Health Week, it seems appropriate to survey what we now know about how gardening and access to green spaces, impacts on our well being. Much of what is “discovered” in scientific research into this topic, will come as no surprise to keen gardeners or those who know them.

Acupuncture in Exeter: gardening and health.In the UK, 87% of households have a garden, and half the adult population in England report gardening as a free time activity: homing in on age ranges, this figure is 40% in the 25-44 age group and 70% for those aged 65-74. Increasing numbers of younger adults would like to grow food. As an indicator of the direction in which gardeners’ interests overall are moving, sales of vegetable seeds have recently exceeded those of flower seeds for the first time since the Second World War.

Acupuncture in Exeter: gardening and health.It has been established that time spent in green spaces is linked to a long-term reduction in reported health problems. This includes heart disease, cancer, musculoskeletal problems, obesity, depression and anxiety. School gardening is linked with a significant increase in fruit and vegetable intake by children. Allotment gardening improves mood and self-esteem, and reduces cortisol levels (a measure of stress) in subjects compared with their matched controls. Studies in Holland, Japan and Canada indicate that for every 10% increase in exposure to green space, people enjoy health equivalent to that of someone five years younger. Living in areas with green spaces is associated with significantly less income-related health inequality.

As we get older, gardening becomes relatively more important as a physical activity. There is emerging evidence of a link with prevention of falls, dementia and cognitive decline.

Acupuncture in Exeter: gardening and health.The NHS is beginning to use social prescribing and community referral, having recognised that social and economic factors play a role in underpinning health: Lambeth GP Food Co-op covers eleven practices where patients with long-term conditions work together to grow food. Horatio’s Garden creates and maintains gardens in NHS spinal injury centres.

So in addition to spending time in your own garden, consider visiting others in the south-west which are open this week under the NGS scheme

(Gardens and health: Implications for policy and practice. The King’s Fund, May 2016.)

Vitamin D Supplements Protect Against Acute Respiratory Tract Infection

Vitamin D Supplements Protect Against Acute Respiratory Tract Infection.
A meta-analysis of 25 double-blind, randomised, controlled trials covering 11 000 participants, has concluded that vitamin D supplementation is both safe and can help provide protection against acute respiratory tract infections.
Participants ranged in age up to 95, and data on a host of factors was assessed, including incidence of infections, their requirement for antibiotics, and number of days off school or work. Trials had taken place in 14 countries across 4 continents. Protective effects were strongest in those who already had profound vitamin D deficiency at baseline.

There were no serious adverse events associated with taking vitamin D. Concerns normally centre around raised blood calcium levels and kidney stones; these were no higher in the vitamin D groups compared to the control groups.

The researchers say their results add to the body of evidence supporting the introduction of public health measures such as food fortification, to improve vitamin D status, particularly in settings where profound vitamin D deficiency is common.

Public Health England recommended in 2016 that everyone needs vitamin D equivalent to an average daily intake of 10 micrograms, although this is intended to protect bone and muscle health.

(Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. British Medical Journal, online 15 February 2017.)

Frequent Saunas Protect Men Against Dementia

Birch logs for a traditional wood-fired sauna: frequent saunas protect men against dementia.
A study carried out at the University of Eastern Finland, suggests that frequent saunas are associated with significantly reduced risk of dementia in men.

The effects of sauna use on the risk of Alzheimer’s disease and other forms of dementia were studied in the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD), which gathered data for 20 years on more than 2000 middle-aged men living in eastern Finland. Based on their sauna useage, participants were divided into three groups: those taking a sauna once a week; those taking one 2–3 times a week; those taking one 4–7 times a week.

The more frequently saunas were taken, the lower was the risk of dementia. Among those taking a sauna 4–7 times a week, the risk of any form of dementia was 66% lower and the risk of Alzheimer’s disease 65% lower than among those taking a sauna just once a week.

Previous results from the KIHD study have shown that frequent sauna bathing also significantly reduces the risk of sudden cardiac death, the risk of death due to coronary artery disease and other cardiac events, as well as overall mortality. According to Professor Jari Laukkanen, the study leader, saunas may protect both the heart and memory to some extent via similar, still poorly known mechanisms. The sense of well-being and relaxation may also play a role.

(University of Eastern Finland, online news, accessed 4 January 2017.)